In case you are dealing with the issues of the MouseMux and want something better that really works - we have discovered ASTER another program that can isolate two or multiple users completely for each other and allow you to share dedicated resources commonly or dedicated to each one of them.
There is a 14 days free trail and then it costs, but in my opinion it worth it - way cheaper than buying two separate PC / MAC computers for e.g. two users.
Also, you can play games at the same time and share multiple monitors (but in this case each user must be dedicated entirely to a video card / mother board displays.
Still, everything works perfectly and smoothly and the users won't interact with each other unless you configure hardware to be shared between them